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Adjuvant activity of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds.

Adjuvant and antitumor activities of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine were examined. All the synthetic 6-O-corynomycoloyl-, 6-O-mocardomycoloyl-, and 6-O-mycoloyl-N-acetylmuramyl-L-alanyl-D-isoglutamine were active as adjuvants for cell-mediated immune responses. Howe...

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Published in:Infect Immun
Main Authors: Azuma, I, Sugimura, K, Yamawaki, M, Uemiya, M, Kusumoto, S, Okada, S, Shiba, T, Yamamura, Y
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1978
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/97234/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.20.3.600-607.1978
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