Patient-Based Transcriptome-Wide Analysis Identify Interferon and Ubiquination Pathways as Potential Predictors of Influenza A Disease Severity

BACKGROUND: The influenza A virus is an RNA virus that is responsible for seasonal epidemics worldwide with up to five million cases of severe illness and 500,000 deaths annually according to the World Health Organization estimates. The factors associated with severe diseases are not well defined, b...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hoang, Long Truong, Tolfvenstam, Thomas, Ooi, Eng Eong, Khor, Chiea Chuen, Naim, Ahmand Nazri Mohamed, Ho, Eliza Xin Pei, Ong, Swee Hoe, Wertheim, Heiman F., Fox, Annette, Van Vinh Nguyen, Chau, Nghiem, Ngoc My, Ha, Tuan Manh, Thi Ngoc Tran, Anh, Tambayah, Paul, Lin, Raymond, Sangsajja, Chariya, Manosuthi, Weerawat, Chuchottaworn, Chareon, Sansayunh, Piamlarp, Chotpitayasunondh, Tawee, Suntarattiwong, Piyarat, Chokephaibulkit, Kulkanya, Puthavathana, Pilaipan, de Jong, Menno D., Farrar, Jeremy, van Doorn, H. Rogier, Hibberd, Martin Lloyd
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218794/
https://ncbi.nlm.nih.gov/pubmed/25365328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111640
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