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RB-02 PHASE I/II CLINICAL TRIAL USING TRANS SODIUM CROCETINATE AS A RADIOSENSITIZER FOR GLIOBLASTOMA

BACKGROUND: Trans sodium crocetinate (TSC) was developed at UVA to increase tissue oxygenation. Since hypoxic tumors are more resistant to radiation therapy (RT), TSC was demonstrated to increase survival in a rat GBM model.TSC has been used in an open GBM clinical trial in conjunction with TMZ and...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Gainer, John, Sheehan, Jason, Larner, James, Jones, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218554/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou271.2
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