IT-32 DIVERGENCE OF INTRATUMORAL AND SYSTEMIC T CELL REPERTOIRES REFLECTS LOCAL MONOCYTE PROFILES DURING GLIOMA PROGRESSION

INTRODUCTION: Glioblastoma (GBM) remains prognostically dismal, with relatively modest gains in survival from conventional therapies motivating research into how its characteristic immunosuppression might be reversed with minimal damage to brain tissue. We sequenced the T cell receptor (TCR) reperto...

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Main Authors: Sims, Jennifer, Grinshpun, Boris, Feng, Yaping, Neira, Justin, Samanamud, Jorge, Amendolara, Benjamin, Canoll, Peter, Sims, Peter, Shen, Yufeng, Bruce, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218250/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.30
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