IT-23 INDUCTION OF ROBUST TYPE-1 CD8(+) T-CELL RESPONSES IN WHO GRADE II LOW-GRADE GLIOMA PATIENTS RECEIVING PEPTIDE-BASED VACCINES IN COMBINATION WITH POLY-ICLC

PURPOSE: WHO grade II low-grade gliomas (LGGs) with high risk factors for recurrence are mostly lethal despite current treatments. We conducted a phase I study to evaluate the safety and immunogenicity of subcutaneous vaccinations with synthetic peptides for glioma-associated antigen (GAA) epitopes...

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Hauptverfasser: Okada, Hideho, Butterfield, Lisa, Hamilton, Ronald, Ahn, Brian, Kohanbash, Gary, Drappatz, Jan, Engh, Johnathan, Amankulor, Nduka, Lively, Mark, Chan, Michael, Salazar, Andres, Shaw, Edward, Potter, Douglas, Lieberman, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218240/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.21
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