DR-07 TARGETING EGFR-VIII WITH DICHLOROACETATE IN TEMOZOLOMIDE RESISTANT GLIOBLASTOMA MODELS

Epidermal growth factor receptor (EGFR) gene amplification and its subsequent over-expression is the most frequent genetic alteration associated with glioblastoma (GBM) approximating 40%. EGFR amplification is accompanied by a gene rearrangement that overexpresses the receptor variant III (EGFRvIII)...

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Detaylı Bibliyografya
Asıl Yazarlar: Velpula, Kiran Kumar, Asuthkar, Swapna, Lathia, Justin D., Tsung, Andrew J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218046/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou252.7
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