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CS-32 SapC-DOPS INDUCES Smac-AND Bax-MEDIATED MITOCHONDRIAL APOPTOSIS IN NEUROBLASTOMAS
SapC-DOPS nanovesicles are a stable protein-lipid mixture assembled from saposin C (SapC) and dioleylphosphatidylserine (DOPS). It shows selective tumor-targeting activity in multiple animal tumor models and specific induction of apoptosis in various cancer cell lines. The preferential targeting is...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217990/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.32 |
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