BM-07 GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS

BACKGROUND: Brain metastases are the most common intracranial tumors in adults. We have a limited understanding of how brain metastases evolve from their primary tumor. Our objectives were to (1) elucidate the evolutionary patterns leading to brain metastases and (2) identify whether brain metastase...

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Auteurs principaux: Brastianos, Priscilla, Carter, Scott, Santagata, Sandro, Taylor-Weiner, Amaro, Jones, Robert, Van Allen, Eli, Horowitz, Peleg, Ligon, Keith, Cahill, Daniel, Dunn, Ian, Van Hummelen, Paul, Lin, Nancy, Curry, William, Stemmer-Rachamimov, Anat, Beroukhim, Rameen, Batchelor, Tracy, Baselga, Jose, Louis, David, Getz, Gad, Hahn, William
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217943/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou240.7
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