BI-30 CHARACTERIZATION OF L1CAM AS A CLINICAL MARKER FOR THE C11orf95-RELA FUSION IN SUPRATENTORIAL EPENDYMOMAS

BACKGROUND: Recently, a novel oncogenic fusion involving C11orf95 and RELA genes was described in a subset of supratentorial ependymoma causing aberrant activation of the NF-κB pathway. METHODS: We evaluated a cohort of 83 supratentorial ependymomas from the CERN tissue repository using RNAseq, RT-P...

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Main Authors: Wani, Khalida, Armstrong, Terri S., Jones, David T., Vera-Bolanos, Elizabeth, Witt, Hendrik, Capper, David, Pfister, Stefan M., Gilbertson, Richard J., Gilbert, Mark R., Aldape, Kenneth
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217899/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou239.30
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