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AI-27 BKM-120: AN ANTI-INVASIVE CANDIDATE FOR THE TREATMENT OF GLIOBLASTOMA
BKM-120 is a selective pan-class I phosphatidyl-inositol-3 kinase (PI3K) inhibitor. BKM-120 can penetrate the blood-brain barrier and it is currently in clinical trials for a several types of solid tumor, including glioblastoma. The PI3K pathway is one of the most commonly deregulated in glioblastom...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217866/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou238.27 |
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