AI-14 THE ANTI ANGIOGENIC AND INVASIVE EFFECTS OF AN INTEGRIN INHIBITOR AGAINST BEVACIZUMAB-INDUCED INVASIVE GLIOMA

Glioblastoma is known to secrete high levels of vascular endothelial growth factor (VEGF), and clinical studies with bevacizumab, a monoclonal antibody to VEGF, have demonstrated convincing therapeutic benefits in patients with glioblastoma. However, its induction of invasive proliferation has also...

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Main Authors: Ishida, Joji, Onishi, Manabu, Kurozumi, Kazuhiko, Ichikawa, Tomotsugu, Fujii, Kentaro, Shimazu, Yosuke, Oka, Tetsuo, Otani, Yoshihiro, Shimizu, Toshihiko, Date, Isao
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217852/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou238.14
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