AT-30 EFFECTS OF EVEROLIMUS ON MENINGIOMA GROWTH IN PATIENTS WITH NEUROFIBROMATOSIS TYPE 2

BACKGROUND: Vestibular schwannomas (VS) and meningiomas are associated with biallelic loss of NF2, and may arise sporadically or in the context of the tumor predisposition syndrome neurofibromatosis type 2. Loss of NF2 activates the mammalian target of rapamycin (mTOR) pathway, and published in vitr...

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Autors principals: Karajannis, Matthias, Osorio, Diana, Filatov, Alexander, Hagiwara, Mari, Mitchell, Carole, Wisoff, Jeffrey, Golfinos, John, Roland, Thomas, Allen, Jeffrey
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217809/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.30
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