AT-25 A PHASE I STUDY OF CONVECTION-ENHANCED DELIVERY OF LIPOSOMAL-IRINOTECAN USING REAL-TIME IMAGING WITH GADOLINIUM IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA

BACKGROUND: Chemotherapy for high grade glioma (HGG) is limited by the blood brain barrier. Convection enhanced delivery (CED) improves chemotherapy delivery by utilizing fluid convection obviating the challenges of crossing the BBB while minimizing systemic toxicity. CED of nanoliposomal irinotecan...

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Huvudupphovsmän: Han, Seunggu, Martin, Alastair, Berger, Mitchel, Prados, Michael, Chang, Susan, Clarke, Jennifer, Bankiewicz, Krystof, Butowski, Nicholas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217803/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.25
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