AT-25 A PHASE I STUDY OF CONVECTION-ENHANCED DELIVERY OF LIPOSOMAL-IRINOTECAN USING REAL-TIME IMAGING WITH GADOLINIUM IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA

BACKGROUND: Chemotherapy for high grade glioma (HGG) is limited by the blood brain barrier. Convection enhanced delivery (CED) improves chemotherapy delivery by utilizing fluid convection obviating the challenges of crossing the BBB while minimizing systemic toxicity. CED of nanoliposomal irinotecan...

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Main Authors: Han, Seunggu, Martin, Alastair, Berger, Mitchel, Prados, Michael, Chang, Susan, Clarke, Jennifer, Bankiewicz, Krystof, Butowski, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217803/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.25
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