AT-23 A PHASE II STUDY OF LAPATINIB AND DOSE-DENSE TEMOZOLOMIDE (TMZ) FOR ADULTS WITH RECURRENT EPENDYMOMA: A CERN CLINICAL TRIAL

BACKGROUND: Ependymoma is an uncommon adult primary CNS tumor. Initial treatment includes extensive resection often followed by but there is no standard treatment for recurrent disease. Molecular studies show most tumors have ErbB2 overexpression and unmethylated MGMT promoter status. We developed a...

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Main Authors: Gilbert, Mark, Yuan, Ying, Wani, Khalida, Wu, Jimin, Omuro, Antonio, Lieberman, Frank, Robins, H. Ian, Gerstner, Elizabeth, Wu, Jing, Wen, Patrick, Mikkelsen, Tom, Armstrong, Terri, Aldape, Ken
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217801/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.23
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