AT-17 RE-ANALYSIS OF PFS/RESPONSE USING ORIGINAL MACDONALD CRITERIA AND RESPONSE EVALUATION CRITERIA IN SOLID TUMORS IN THE PHASE III AVAGLIO STUDY OF BEVACIZUMAB PLUS RADIOTHERAPY AND TEMOZOLOMIDE IN NEWLY DIAGNOSED GLIOBLASTOMA

BACKGROUND: AVAglio: bevacizumab (BEV) plus radiotherapy (RT) plus temozolomide (TMZ) extended investigator-assessed PFS versus placebo + RT/TMZ (HR = 0.64, p < 0.0001, median 10.6 vs 6.2 months). AVAglio response criteria were similar to Response Assessment in Neuro-Oncology (i.e. included T2/fl...

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Main Authors: Chinot, Olivier L., Wick, Wolfgang, van den Bent, Martin J., Mason, Warren, Henriksson, Roger, Saran, Frank, Nishikawa, Ryo, Revil, Cedric, Kerloeguen, Yannick, Cloughesy, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217794/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.17
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