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Established Monolayer Differentiation of Mouse Embryonic Stem Cells Generates Heterogeneous Neocortical-Like Neurons Stalled at a Stage Equivalent to Midcorticogenesis

Two existing and widely applied protocols of embryonic stem (ES) cell differentiation have been developed to enable in vitro generation of neurons resembling neocortical projection neurons in monolayer culture and from embryoid bodies. The monolayer approach offers advantages for detailed in vitro c...

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Библиографические подробности
Главные авторы: Sadegh, Cameron, Macklis, Jeffrey D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217685/
https://ncbi.nlm.nih.gov/pubmed/24610556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23576
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