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The Promise of Patient-Derived Xenografts: The best laid plans of mice and men

Compared to xenografts from previously established cell-lines, patient-derived xenografts may more faithfully recapitulate the molecular diversity, cellular heterogeneity, and histology seen in patient tumors, although other limitations of murine models remain. The ability of these models to inform...

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Autores principales: Kopetz, Scott, Lemos, Robert, Powis, Garth
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217576/
https://ncbi.nlm.nih.gov/pubmed/22912394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2408
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