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Reduced Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor Is Associated With Cognitive Impairment in Late-Life Major Depression

OBJECTIVES. Late-life depression (LLD) is associated with reduced neurotrophic support and abnormalities in neurodegenerative cascades. The aim of the present study is to determine the concentrations of brain-derived neurotrophic factor (BDNF), amyloid-β(42), total Tau, and phosphorylated Tau in the...

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Autores principales: Diniz, Breno S., Teixeira, Antonio L., Machado-Vieira, Rodrigo, Talib, Leda L., Radanovic, Marcia, Gattaz, Wagner F., Forlenza, Orestes V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217554/
https://ncbi.nlm.nih.gov/pubmed/25149921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geronb/gbu096
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