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Genome-wide analysis of non-coding regulatory mutations in cancer
Cancer primarily develops due to somatic alterations in the genome. Advances in sequencing have enabled large-scale sequencing studies across many tumor types, emphasizing discovery of alterations in protein-coding genes. However, the protein-coding exome comprises less than 2% of the human genome....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217527/ https://ncbi.nlm.nih.gov/pubmed/25261935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3101 |
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