Elevated activation of CaMKIIα in the CPEB3-knockout hippocampus impairs a specific form of NMDAR-dependent synaptic depotentiation

Cytoplasmic polyadenylation element binding protein 3 (CPEB3) is a sequence-specific RNA-binding protein that confines the strength of glutamatergic synapses by translationally downregulating the expression of multiple plasticity-related proteins (PRPs), including the N-methyl-D-aspartate receptor (...

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Main Authors: Huang, Wen-Hsuan, Chao, Hsu-Wen, Tsai, Li-Yun, Chung, Ming-Hung, Huang, Yi-Shuian
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2014
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217494/
https://ncbi.nlm.nih.gov/pubmed/25404896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00367
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