Adeno-Associated Virus-Like Particles as New Carriers for B-Cell Vaccines: Testing Immunogenicity and Safety in BALB/c Mice

Adeno-associated viruses (AAVs) are established vectors for gene therapy of different human diseases. AAVs are assembled of 60 capsomers, which can be genetically modified, allowing high-density display of short peptide sequences at their surface. The aim of our study was to evaluate the immunogenic...

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Hlavní autoři: Manzano-Szalai, Krisztina, Thell, Kathrin, Willensdorfer, Anna, Weghofer, Margit, Pfanzagl, Beatrix, Singer, Josef, Ritter, Mirko, Stremnitzer, Caroline, Flaschberger, Ingo, Michaelis, Uwe, Jensen-Jarolim, Erika
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2014
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217042/
https://ncbi.nlm.nih.gov/pubmed/25247267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2014.0059
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