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A near-infrared fluorescent voltage-sensitive dye allows for moderate-throughput electrophysiological analyses of human induced pluripotent stem cell-derived cardiomyocytes
Human induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM)-based assays are emerging as a promising tool for the in vitro preclinical screening of QT interval-prolonging side effects of drugs in development. A major impediment to the widespread use of human iPSC-CM assays is the low through...
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主要な著者: | , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Physiological Society
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217013/ https://ncbi.nlm.nih.gov/pubmed/25172899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00344.2014 |
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