A near-infrared fluorescent voltage-sensitive dye allows for moderate-throughput electrophysiological analyses of human induced pluripotent stem cell-derived cardiomyocytes

Human induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM)-based assays are emerging as a promising tool for the in vitro preclinical screening of QT interval-prolonging side effects of drugs in development. A major impediment to the widespread use of human iPSC-CM assays is the low through...

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Autori principali: Lopez-Izquierdo, Angelica, Warren, Mark, Riedel, Michael, Cho, Scott, Lai, Shuping, Lux, Robert L., Spitzer, Kenneth W., Benjamin, Ivor J., Tristani-Firouzi, Martin, Jou, Chuanchau J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
Soggetti:
Integrative Cardiovascular Physiology and Pathophysiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217013/
https://ncbi.nlm.nih.gov/pubmed/25172899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00344.2014
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