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Shear stress-related mechanosignaling with lung ischemia: lessons from basic research can inform lung transplantation

Cessation of blood flow represents a physical event that is sensed by the pulmonary endothelium leading to a signaling cascade that has been termed “mechanotransduction.” This paradigm has clinical relevance for conditions such as pulmonary embolism, lung bypass surgery, and organ procurement and st...

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Main Authors: Chatterjee, Shampa, Nieman, Gary F., Christie, Jason D., Fisher, Aron B.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217004/
https://ncbi.nlm.nih.gov/pubmed/25239915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00198.2014
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