Insulin secretion stimulated by l-arginine and its metabolite l-ornithine depends on Gα(i2)

Bordetella pertussis toxin (PTx), also known as islet-activating protein, induces insulin secretion by ADP-ribosylation of inhibitory G proteins. PTx-induced insulin secretion may result either from inactivation of Gα(o) proteins or from combined inactivation of Gα(o), Gα(i1), Gα(i2), and Gα(i3) iso...

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Detalhes bibliográficos
Main Authors: Leiss, Veronika, Flockerzie, Katarina, Novakovic, Ana, Rath, Michaela, Schönsiegel, Annika, Birnbaumer, Lutz, Schürmann, Annette, Harteneck, Christian, Nürnberg, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216945/
https://ncbi.nlm.nih.gov/pubmed/25205820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00337.2014
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