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Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

We have previously demonstrated that Stat3 regulates lysosomal mediated-programmed cell death (LM-PCD) during mouse mammary gland involution in vivo. However, the mechanism that controls the release of lysosomal cathepsins to initiate cell death in this context has not been elucidated. We show here...

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Detalhes bibliográficos
Main Authors: Sargeant, Timothy J., Lloyd-Lewis, Bethan, Resemann, Henrike K., Ramos-Montoya, Antonio, Skepper, Jeremy, Watson, Christine J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216597/
https://ncbi.nlm.nih.gov/pubmed/25283994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3043
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