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In COS Cells Vpu Can Both Stabilize Tetherin Expression and Counteract Its Antiviral Activity
The interferon-inducible cellular protein tetherin (CD317/BST-2) inhibits the release of a broad range of enveloped viruses. The HIV-1 accessory protein Vpu enhances virus particle release by counteracting this host restriction factor. While the antagonism of human tetherin by Vpu has been associate...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4216104/ https://ncbi.nlm.nih.gov/pubmed/25360760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111628 |
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