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LRRK2 Transport Is Regulated by Its Novel Interacting Partner Rab32

Leucine-rich repeat kinase 2 (LRRK2) is a multi-domain 280 kDa protein that is linked to Parkinson's disease (PD). Mutations especially in the GTPase and kinase domains of LRRK2 are the most common causes of heritable PD and are also found in sporadic forms of PD. Although the cellular function...

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Detalhes bibliográficos
Main Authors: Waschbüsch, Dieter, Michels, Helen, Strassheim, Swantje, Ossendorf, Edith, Kessler, Daniel, Gloeckner, Christian Johannes, Barnekow, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216093/
https://ncbi.nlm.nih.gov/pubmed/25360523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111632
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