Polymorphisms of an Innate Immune Gene, Toll-Like Receptor 4, and Aggressive Prostate Cancer Risk: A Systematic Review and Meta-Analysis

BACKGROUND: Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. The role of TLR4 in the pathophysiology of several age-related diseases...

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Autori principali: Weng, Pei-Hsuan, Huang, Yi-Ling, Page, John H., Chen, Jen-Hau, Xu, Jianfeng, Koutros, Stella, Berndt, Sonja, Chanock, Stephen, Yeager, Meredith, Witte, John S., Eeles, Rosalind A., Easton, Douglas F., Neal, David E., Donovan, Jenny, Hamdy, Freddie C., Muir, Kenneth R., Giles, Graham, Severi, Gianluca, Smith, Jeffrey R., Balistreri, Carmela R., Shui, Irene M., Chen, Yen-Ching
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215920/
https://ncbi.nlm.nih.gov/pubmed/25360682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110569
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