Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones

We have assessed, using whole-cell patch-clamp recording and RNA-sequencing (RNA-seq), the properties and composition of GABA(A) receptors (GABA(A)Rs) and strychnine-sensitive glycine receptors (GlyRs) expressed by excitatory cortical neurons derived from human embryonic stem cells (hECNs). The agon...

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Detalhes bibliográficos
Main Authors: James, Owain T, Livesey, Matthew R, Qiu, Jing, Dando, Owen, Bilican, Bilada, Haghi, Ghazal, Rajan, Rinku, Burr, Karen, Hardingham, Giles E, Chandran, Siddharthan, Kind, Peter C, Wyllie, David J A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Neuroscience: Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215781/
https://ncbi.nlm.nih.gov/pubmed/25172951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.278994
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