Osmotic activation of phospholipase C triggers structural adaptation in osmosensitive rat supraoptic neurons

The magnocellular neurosecretory cells of the hypothalamus (MNCs) synthesize and secrete vasopressin or oxytocin. A stretch-inactivated cation current mediated by TRPV1 channels rapidly transduces increases in external osmolality into a depolarization of the MNCs leading to an increase in action pot...

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Bibliografiske detaljer
Main Authors: Shah, Love, Bansal, Vimal, Rye, Peter L, Mumtaz, Naima, Taherian, Amir, Fisher, Thomas E
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2014
Fag:
Neuroscience: Cellular/Molecular
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215769/
https://ncbi.nlm.nih.gov/pubmed/25015921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.273813
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