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The ‘SAR Matrix’ method and its extensions for applications in medicinal chemistry and chemogenomics

We describe the ‘Structure-Activity Relationship (SAR) Matrix’ (SARM) methodology that is based upon a special two-step application of the matched molecular pair (MMP) formalism. The SARM method has originally been designed for the extraction, organization, and visualization of compound series and a...

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Bibliografiska uppgifter
Huvudupphovsmän: Gupta-Ostermann, Disha, Bajorath, Jürgen
Materialtyp: Artigo
Språk:Inglês
Publicerad: F1000Research 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215758/
https://ncbi.nlm.nih.gov/pubmed/25383183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.4185.2
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