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Subunit composition of the human cytoplasmic dynein-2 complex

Cytoplasmic dynein-2 is the motor for retrograde intraflagellar transport (IFT), and mutations in dynein-2 are known to cause skeletal ciliopathies. Here, we define for the first time the composition of the human cytoplasmic dynein-2 complex. We show that the proteins encoded by the ciliopathy genes...

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Autors principals: Asante, David, Stevenson, Nicola L., Stephens, David J.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215718/
https://ncbi.nlm.nih.gov/pubmed/25205765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.159038
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