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Inputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stress
Oxidative stress can cause DNA breaks which induce activation of the DNA nick sensor enzyme poly(ADP-ribose) polymerase-1 (PARP-1), part of the 17 member PARP enzyme family. PARP-1 modifies target proteins by attaching to them several NAD-derived ADP-ribose units forming poly(ADP-ribose) (PAR) polym...
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| Udgivet i: | Redox Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215470/ https://ncbi.nlm.nih.gov/pubmed/25460733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.08.003 |
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