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Coordination of insulin and Notch pathway activities by microRNA miR-305 mediates adaptive homeostasis in the intestinal stem cells of the Drosophila gut

Homeostasis of the intestine is maintained by dynamic regulation of a pool of intestinal stem cells. The balance between stem cell self-renewal and differentiation is regulated by the Notch and insulin signaling pathways. Dependence on the insulin pathway places the stem cell pool under nutritional...

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Autors principals: Foronda, David, Weng, Ruifen, Verma, Pushpa, Chen, Ya-Wen, Cohen, Stephen M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215186/
https://ncbi.nlm.nih.gov/pubmed/25367037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.241588.114
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