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Postnatal Acquisition of Primary Rhesus Cytomegalovirus Infection is Associated With Prolonged Virus Shedding and Impaired CD4(+) T Lymphocyte Function

Background. Although virus-specific CD4(+) T lymphocytes emerge rapidly during primary cytomegalovirus (CMV) infection in humans, they exhibit a state of prolonged functional exhaustion of unknown etiology. To investigate the suitability of rhesus macaques as a model of primary human CMV infection,...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Antoine, Pierre, Varner, Valerie, Carville, Angela, Connole, Michelle, Marchant, Arnaud, Kaur, Amitinder
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215082/
https://ncbi.nlm.nih.gov/pubmed/24719473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu215
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