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Antigen-Presenting Phagocytic Cells Ingest Malaria Parasites and Increase HIV Replication in a Tumor Necrosis Factor α-Dependent Manner

Background. Plasmodium falciparum infection induces human immunodeficiency virus (HIV) replication and accelerates a decline in CD4(+) T-cell count. The mechanisms contributing to these interactions have not been fully elucidated. Methods. We infected peripheral blood mononuclear cells (PBMCs) with...

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Detalhes bibliográficos
Main Authors: Orlov, Marika, Vaida, Florin, Williamson, Kathryn, Deng, Qianqian, Smith, David M., Duffy, Patrick E., Schooley, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215075/
https://ncbi.nlm.nih.gov/pubmed/24903666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu317
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