“First-Wave” Bias When Conducting Active Safety Monitoring of Newly Marketed Medications with Outcome-Indexed Self-Controlled Designs

Large health care databases are used extensively for pharmacoepidemiologic studies. Unique methodological issues arise when applying self-controlled designs (i.e., using within-person comparisons) for active surveillance of newly marketed drugs. We use 3 examples to illustrate bias related to popula...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Shirley V., Schneeweiss, Sebastian, Maclure, Malcolm, Gagne, Joshua J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Practice of Epidemiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215070/
https://ncbi.nlm.nih.gov/pubmed/25086050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwu162
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