Carboxypeptidase B serves as a protective mediator in osteoarthritis

OBJECTIVE: We previously demonstrated that carboxypeptidase B (CPB) protects against joint erosion in rheumatoid arthritis by inactivating complement component C5a. We also found that levels of CPB are abnormally high in the synovial fluid of individuals with another joint disease, osteoarthritis (O...

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Autors principals: Lepus, Christin M., Song, Jason J., Wang, Qian, Wagner, Catriona A., Lindstrom, Tamsin M., Chu, Constance R., Sokolove, Jeremy, Leung, Lawrence L., Robinson, William H.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215006/
https://ncbi.nlm.nih.gov/pubmed/24449579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38213
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