Oral Lovastatin Attenuates Airway Inflammation and Mucus Secretion in Ovalbumin-Induced Murine Model of Asthma

PURPOSE: Lovastatin is an effective inhibitor of cholesterol synthesis. A previous study demonstrated that lovastatin can also suppress airway hyperresponsiveness (AHR) in murine model of asthma. We aimed to investigate the effect of lovastatin on mucus secretion and inflammation-associated gene exp...

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Bibliografiske detaljer
Main Authors: Liou, Chian-Jiun, Cheng, Pei-Yun, Huang, Wen-Chung, Chan, Cheng-Chi, Chen, Meng-Chun, Kuo, Ming-Ling, Shen, Jiann-Jong
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214976/
https://ncbi.nlm.nih.gov/pubmed/25374755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2014.6.6.548
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