The ESAT-6 Protein of Mycobacterium tuberculosis Interacts with Beta-2-Microglobulin (β2M) Affecting Antigen Presentation Function of Macrophage

ESAT-6, an abundantly secreted protein of Mycobacterium tuberculosis (M. tuberculosis) is an important virulence factor, inactivation of which leads to reduced virulence of M. tuberculosis. ESAT-6 alone, or in complex with its chaperone CFP-10 (ESAT-6:CFP-10), is known to modulate host immune respon...

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Główni autorzy: Sreejit, Gopalkrishna, Ahmed, Asma, Parveen, Nazia, Jha, Vishwanath, Valluri, Vijaya Lakshmi, Ghosh, Sudip, Mukhopadhyay, Sangita
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2014
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214792/
https://ncbi.nlm.nih.gov/pubmed/25356553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004446
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