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Glycolysis-dependent histone deacetylase 4 degradation regulates inflammatory cytokine production
Activation of the inflammatory response is accompanied by a metabolic shift to aerobic glycolysis. Here we identify histone deacetylase 4 (HDAC4) as a new component of the immunometabolic program. We show that HDAC4 is required for efficient inflammatory cytokine production activated by lipopolysacc...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4214777/ https://ncbi.nlm.nih.gov/pubmed/25187650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-12-0757 |
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