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Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K(2P)) mechano-gated potassium channel

The mechanisms of mechanosensitivity underlying the response of the human bladder to stretch are poorly understood. Animal data suggest that stretch-activated two-pore-domain (K(2P)) K(+) channels play a critical role in bladder relaxation during the filling phase. The objective of this study was to...

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Autors principals: Lei, Qi, Pan, Xiao-Qing, Chang, Shaohua, Malkowicz, S Bruce, Guzzo, Thomas J, Malykhina, Anna P
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214657/
https://ncbi.nlm.nih.gov/pubmed/24801307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.271718
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