FuseFISH: Robust Detection of Transcribed Gene Fusions in Single Cells

Transcribed gene fusions are key biomarkers in many hematologic and solid tumors, often representing the primary oncogenic driver mutation. Here, we report an experimental and computational pipeline for detecting fusion transcripts using single-molecule RNA FISH and unbiased correlation analysis (Fu...

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Hauptverfasser: Semrau, Stefan, Crosetto, Nicola, Bienko, Magda, Boni, Marina, Bernasconi, Bernasconi, Chiarle, Roberto, van Oudenaarden, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214547/
https://ncbi.nlm.nih.gov/pubmed/24373969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.002
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