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FuseFISH: Robust Detection of Transcribed Gene Fusions in Single Cells

Transcribed gene fusions are key biomarkers in many hematologic and solid tumors, often representing the primary oncogenic driver mutation. Here, we report an experimental and computational pipeline for detecting fusion transcripts using single-molecule RNA FISH and unbiased correlation analysis (Fu...

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Detalhes bibliográficos
Main Authors: Semrau, Stefan, Crosetto, Nicola, Bienko, Magda, Boni, Marina, Bernasconi, Bernasconi, Chiarle, Roberto, van Oudenaarden, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214547/
https://ncbi.nlm.nih.gov/pubmed/24373969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.002
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