Sex hormone pathway gene polymorphisms are associated with risk of advanced hepatitis C-related liver disease in males

Background: Males have excess advanced liver disease and cirrhosis risk including from chronic hepatitis C virus (HCV) infection though the reasons are unclear. Goal: To examine the role variants in genes involved in androgen and estrogen biosynthesis and metabolism play in HCV-related liver disease...

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Main Authors: White, Donna L, Liu, Yanhong, Garcia, Jose, El-Serag, Hashem B, Jiao, Li, Tsavachidis, Spiridon, Franco, Luis M, Lee, Ju-Seog, Tavakoli-Tabasi, Shahriar, Moore, David, Goldman, Radoslav, Kuzniarek, Jill, Ramsey, David J, Kanwal, Fasiha, Marcelli, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214264/
https://ncbi.nlm.nih.gov/pubmed/25379136
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