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Compressive Stress Inhibits Proliferation in Tumor Spheroids through a Volume Limitation

In most instances, the growth of solid tumors occurs in constrained environments and requires a competition for space. A mechanical crosstalk can arise from this competition. In this article, we dissect the biomechanical sequence caused by a controlled compressive stress on multicellular spheroids (...

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Auteurs principaux: Delarue, Morgan, Montel, Fabien, Vignjevic, Danijela, Prost, Jacques, Joanny, Jean-François, Cappello, Giovanni
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213738/
https://ncbi.nlm.nih.gov/pubmed/25418163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.08.031
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