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Selection of influenza B virus recombinants and their testing in humans for attenuation and immunogenicity.

The selection of influenza B virus recombinants from plaques in bovine kidney cell monolayers is described. Two sets of recombinants were each derived from parents of high and low virulence for humans, respectively. Recombination frequency was apparently high, and reassortment of genes made it possi...

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Autors principals: Beare, A S, Sherwood, J E, Callow, K A, Craig, J W
Format: Artigo
Idioma:Inglês
Publicat: 1977
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC421373/
https://ncbi.nlm.nih.gov/pubmed/844900
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