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Comparative metabolism as a key driver of wildlife species sensitivity to human and veterinary pharmaceuticals
Human and veterinary drug development addresses absorption, distribution, metabolism, elimination and toxicology (ADMET) of the Active Pharmaceutical Ingredient (API) in the target species. Metabolism is an important factor in controlling circulating plasma and target tissue API concentrations and i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4213593/ https://ncbi.nlm.nih.gov/pubmed/25405970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0583 |
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