Defective IL-17- and IL-22-dependent mucosal host response to Candida albicans determines susceptibility to oral candidiasis in mice expressing the HIV-1 transgene

BACKGROUND: The tissue-signaling cytokines IL-17 and IL-22 are critical to host defense against oral Candida albicans infection, by their induction of oral antimicrobial peptide expression and recruitment of neutrophils. Mucosal Th17 cells which produce these cytokines are preferentially depleted in...

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Detalhes bibliográficos
Main Authors: Goupil, Mathieu, Cousineau-Côté, Vincent, Aumont, Francine, Sénéchal, Serge, Gaboury, Louis, Hanna, Zaher, Jolicoeur, Paul, de Repentigny, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213580/
https://ncbi.nlm.nih.gov/pubmed/25344377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0049-9
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