Defective IL-17- and IL-22-dependent mucosal host response to Candida albicans determines susceptibility to oral candidiasis in mice expressing the HIV-1 transgene

BACKGROUND: The tissue-signaling cytokines IL-17 and IL-22 are critical to host defense against oral Candida albicans infection, by their induction of oral antimicrobial peptide expression and recruitment of neutrophils. Mucosal Th17 cells which produce these cytokines are preferentially depleted in...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Goupil, Mathieu, Cousineau-Côté, Vincent, Aumont, Francine, Sénéchal, Serge, Gaboury, Louis, Hanna, Zaher, Jolicoeur, Paul, de Repentigny, Louis
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213580/
https://ncbi.nlm.nih.gov/pubmed/25344377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0049-9
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