KSHV miRNAs Decrease Expression of Lytic Genes in Latently Infected PEL and Endothelial Cells by Targeting Host Transcription Factors

Kaposi’s sarcoma-associated herpesvirus (KSHV) microRNAs are encoded in the latency-associated region. Knockdown of KSHV miR-K12-3 and miR-K12-11 increased expression of lytic genes in BC-3 cells, and increased virus production from latently infected BCBL-1 cells. Furthermore, iSLK cells infected wi...

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Bibliografiske detaljer
Main Authors: Plaisance-Bonstaff, Karlie, Choi, Hong Seok, Beals, Tyler, Krueger, Brian J., Boss, Isaac W., Gay, Lauren A., Haecker, Irina, Hu, Jianhong, Renne, Rolf
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213575/
https://ncbi.nlm.nih.gov/pubmed/25341664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6104005
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